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Safety guide · Roux-en-Y gastric bypass

Gastric Bypass Side Effects and Complications

Serious complications after gastric bypass are uncommon, but every surgery has risks. This guide covers what can happen in the first weeks and the years after, which symptoms need a call to your care team, and how to lower your risk.

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The big picture

How safe is gastric bypass?

In US data, gastric bypass carried slightly more short-term risk than the gastric sleeve. Over the long term, it led to more weight loss and less reflux damage than the sleeve in the 10-year SLEEVEPASS trial.

0.2%Died within 30 days, among 43,354 US gastric bypass patients (0.1% after sleeve).El Chaar et al., MBSAQIP 30-day outcomes, 2018
2.5%Needed another operation within 30 days, vs 1.0% after sleeve.El Chaar et al., MBSAQIP 30-day outcomes, 2018
2.8%Were readmitted to the hospital within 30 days, vs 1.2% after sleeve.El Chaar et al., MBSAQIP 30-day outcomes, 2018

The first weeks

Short-term risks after surgery

These risks are similar to any abdominal surgery: bleeding, infection, reactions to anesthesia, blood clots, leaks and diarrhea (Mayo Clinic).

Leaks

A leak where the pouch joins the intestine is one of the most serious complications. It usually shows up within a few days but can take weeks. Signs include fever, a fast heart rate, belly or left shoulder pain, and vomiting.

Blood clots

Clots can form in the legs (deep vein thrombosis) or travel to the lungs (pulmonary embolism). You get compression stockings and blood thinners to lower the risk.

Wound infection

Red, hot or swollen skin, pain around a wound, or pus. It is usually treated with antibiotics.

Bleeding

Bleeding inside the abdomen or the digestive tract, which your care team watches for during your hospital stay.

Months and years later

Long-term side effects and complications

What it isHow commonWhat helps
Dumping syndromeFood moves too quickly into the small intestine. Early dumping comes within 30 minutes of eating; late dumping comes 1 to 3 hours after, with low blood sugar (NIDDK)Up to 40% after bypass (consensus)Changing how and what you eat comes first. Our nutritionists help you adjust portions and food choices
Marginal ulcersAn ulcer where the pouch joins the small intestine. Most appear in the first year0.9% at 1 year to 11.4% over 8 years in large studies (ASMBS)Don’t smoke, ask before taking NSAIDs such as ibuprofen, and take acid-reducing medication (PPI) for at least 3 months
Internal hernia and bowel obstructionA loop of intestine slips through a gap created during surgery and can become blocked2% when the gaps are closed during surgery, vs 6% when they aren’t (meta-analysis)Get urgent care for cramping belly pain, especially after eating
Nutrient deficienciesLower absorption of iron, vitamin B12, calcium and vitamin D, which can cause anemia, fatigue, nerve problems and bone lossExpected without supplementsA multivitamin with iron, calcium and B12 for life, plus regular labs (Mayo Clinic)
Gallstones and kidney stonesStones in the gallbladder or kidneysListed among longer-term risks (Mayo Clinic)Regular follow-up. Tell your doctor about new belly or back pain
Alcohol problemsAlcohol-use problems become more common after bypass20.8% had new alcohol-use-disorder symptoms within 5 years, vs 11.3% after banding (LABS-2)Talk with your care team before drinking, and ask for help early

Regaining weight? That isn’t a complication you have to live with. The outlet from your pouch can stretch over time, and options include TORe and GLP-1 medication. See revision options. Mini gastric bypass has a different risk profile, with more reflux. About mini gastric bypass.

When to get help

Symptoms that need a call to your care team

Call your doctor or your Renew coordinator right away if you notice any of these. If symptoms are severe, go to the nearest emergency room.

Fever or a fast heart rate

Especially with belly or left shoulder pain in the first weeks, which can signal a leak.

Vomiting

Vomiting after eating or drinking, or not being able to keep liquids down. The opening can narrow (stomal stenosis), and it is treatable.

Leg swelling or chest pain

Swelling, warmth or pain in a calf, shortness of breath, or sharp chest pain can mean a blood clot.

Severe or cramping belly pain

Pain that comes in waves or after eating can point to an ulcer or internal hernia.

Wound changes

Redness, heat, swelling or pus around an incision.

Shaky or faint after meals

Sweating, a racing heart or dizziness after eating may be dumping or low blood sugar.

Before and after surgery

How to lower your risk

Stop smoking

Smoking raises the risk of ulcers, and ASMBS advises quitting before gastric bypass (ASMBS).

Take your vitamins

Every day, for life, with the regular labs your care team orders.

Follow the staged diet

Liquids first, then pureed, soft and firmer foods as you heal. See the recovery timeline.

Keep your follow-ups

Our nutritionists stay with you after you go home. Tell them about any new symptoms early.

Have questions about your health history?

Send it to us and our surgeons will review your risks before recommending a procedure. Virtual consultations are available.

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Frequently asked questions

What are the most common side effects of gastric bypass?

Dumping syndrome, nausea, vomiting, diarrhea and nutrient deficiencies are among the most common. Most can be managed with diet changes, vitamins and follow-up care.

How safe is gastric bypass?

In a study of 43,354 US gastric bypass patients, 0.2% died within 30 days and 2.5% needed another operation. Short-term risk is slightly higher than with the gastric sleeve.

What is dumping syndrome?

Dumping syndrome happens when food moves too quickly into the small intestine. Early dumping comes within 30 minutes of eating, and late dumping comes 1 to 3 hours after, with low blood sugar. Changing how and what you eat is the first step in treating it.

How can I prevent ulcers after gastric bypass?

Don’t smoke, ask your doctor before taking NSAIDs such as ibuprofen, and take acid-reducing medication as prescribed. ASMBS recommends a PPI for at least 3 months after surgery.

Do I need vitamins for life after gastric bypass?

Yes. You will need a multivitamin with iron, calcium and vitamin B12 every day, plus regular labs to check your levels.

Can I drink alcohol after gastric bypass?

Talk with your care team first. In the LABS-2 study, 20.8% of gastric bypass patients developed new alcohol-use-disorder symptoms within 5 years.

Related gastric bypass pages

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